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a(CHEBI:"(+)-artemisinin")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
(+)-artemisinin
Namespace
chebi
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/chebi-names.belns

Appears in Networks 2

Inflammasome activation and innate immunity in Alzheimer’s disease v1.0.2

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer’s disease v1.0.0

In-Edges 0

Out-Edges 6

a(CHEBI:"(+)-artemisinin") decreases complex(GO:"NLRP3 inflammasome complex") View Subject | View Object

Using a similar mouse model, Shi et al. treated animals with the antimalarial drug artemisinin, showing that this treatment results in inhibition of NFkB and presumably the NLRP3 inflammasome (13) PubMed:28019679

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons
NeuroMMSigDB
Nuclear factor Kappa beta subgraph

a(CHEBI:"(+)-artemisinin") decreases p(MGI:Nfkbia) View Subject | View Object

Using a similar mouse model, Shi et al. treated animals with the antimalarial drug artemisinin, showing that this treatment results in inhibition of NFkB and presumably the NLRP3 inflammasome (13) PubMed:28019679

Appears in Networks:
Annotations
Confidence
High
MeSH
Neurons
NeuroMMSigDB
Nuclear factor Kappa beta subgraph

a(CHEBI:"(+)-artemisinin") decreases path(MESH:Inflammation) View Subject | View Object

Moreover,it reveals promising anti-inflammatory actions through suppress-ing the activation of NF-B [238–240]. PubMed:29179999

Appears in Networks:

a(CHEBI:"(+)-artemisinin") decreases act(p(FPLX:NFkappaB)) View Subject | View Object

Moreover,it reveals promising anti-inflammatory actions through suppress-ing the activation of NF-B [238–240]. PubMed:29179999

Appears in Networks:

a(CHEBI:"(+)-artemisinin") decreases a(CHEBI:"amyloid-beta") View Subject | View Object

The expression of A was lowered by artemisinin through inhibition of the activity of NALP3 inflammasome in APPswe/PS1E9 transgenic mice [241]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(CHEBI:"(+)-artemisinin") decreases bp(GO:"NLRP3 inflammasome complex assembly") View Subject | View Object

The expression of A was lowered by artemisinin through inhibition of the activity of NALP3 inflammasome in APPswe/PS1E9 transgenic mice [241]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.