1. Catalog
  2. Nodes
  3. bp(GO:"neuron-neuron synaptic transmission")

bp(GO:"neuron-neuron synaptic transmission")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
neuron-neuron synaptic transmission
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 3

Chaperoning α7 neuronal nicotinic acetylcholine receptors v1.0.0

Tau Modifications v1.9.5

Tau Modifications Sections of NESTOR

mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders v1.0.0

In-Edges 5

p(HGNC:CHRNA7) regulates bp(GO:"neuron-neuron synaptic transmission") View Subject | View Object

α7 AChRs can act at the presynaptic, postsynaptic or perisynaptic levels to facilitate the liberation of neurotransmitters, mediate synaptic transmission, or modulate the connections of different neurons by activating diverse second messenger routes [1,19,23–31]. PubMed:22040696

Appears in Networks:

p(HGNC:CAMKV) regulates bp(GO:"neuron-neuron synaptic transmission") View Subject | View Object

These findings suggest that CaMKv is required for both synaptic transmission and protein synthesis-dependent LTP in the hippocampus. PubMed:27796283

Appears in Networks:
Annotations
Uberon
hippocampal formation

bp(GO:"cytoskeleton organization") increases bp(GO:"neuron-neuron synaptic transmission") View Subject | View Object

Alterations in MAP2 immunoreactivity within the subiculum, entorhinal cortex, hippocampus, and prefrontal cortex have been suggested as the primary array of cytoskeletal abnormalities, which in turn result in impaired neurotransmission observed in schizophrenia PubMed:30061532

Appears in Networks:
Annotations
MeSH
Entorhinal Cortex
MeSH
Hippocampus
MeSH
Prefrontal Cortex

complex(p(HGNC:ERBB4), p(HGNC:NRG1)) regulates bp(GO:"neuron-neuron synaptic transmission") View Subject | View Object

In particular, NRG1, which is mostly involved in regulating neurodevelopment and neurotransmission, acts by binding ErbB4, a type I transmembrane receptor tyrosine kinase belonging to the family of ErbB proteins, which contain a binding site for PI3K kinase, an AKT upstream effector, in the C-terminal cytoplasmic tail (CYT) PubMed:30061532

Appears in Networks:

path(MESH:Schizophrenia) negativeCorrelation bp(GO:"neuron-neuron synaptic transmission") View Subject | View Object

Alterations in MAP2 immunoreactivity within the subiculum, entorhinal cortex, hippocampus, and prefrontal cortex have been suggested as the primary array of cytoskeletal abnormalities, which in turn result in impaired neurotransmission observed in schizophrenia PubMed:30061532

Appears in Networks:
Annotations
MeSH
Entorhinal Cortex
MeSH
Hippocampus
MeSH
Prefrontal Cortex

Out-Edges 1

bp(GO:"neuron-neuron synaptic transmission") negativeCorrelation path(MESH:Schizophrenia) View Subject | View Object

Alterations in MAP2 immunoreactivity within the subiculum, entorhinal cortex, hippocampus, and prefrontal cortex have been suggested as the primary array of cytoskeletal abnormalities, which in turn result in impaired neurotransmission observed in schizophrenia PubMed:30061532

Appears in Networks:
Annotations
MeSH
Entorhinal Cortex
MeSH
Hippocampus
MeSH
Prefrontal Cortex

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.