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a(MESH:Exosomes)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Exosomes
Namespace
mesh
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/mesh-names.belns

Appears in Networks 2

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage v1.0.0

Tau oligomers-Cytotoxicity, propagation, and mitochondrial damage from Shafiei et al., 2017

Extracellular Tau and Its Potential Role in the Propagation of Tau Pathology v1.0.0

In-Edges 4

sec(p(HGNC:MAPT)) association a(MESH:Exosomes) View Subject | View Object

Recently, more evidence implies that the secretion of tau occurs through unconventional cellular pathways via vesicles known as exosomes (Saman et al., 2012) and ectosomes (Dujardin et al., 2014a) PubMed:28420982

Appears in Networks:
Annotations
Confidence
High
MeSH
Neocortex

p(HGNC:MAPT, pmod(Ph, Thr, 181)) association a(MESH:Exosomes) View Subject | View Object

In support, tau associated with exosomes and phosphorylated at Thr-181 (AT270+ tau) has been identified in human CSF samples of AD patients PubMed:28420982

Appears in Networks:
Annotations
Confidence
High
MeSH
Cerebrospinal Fluid
MeSH
Alzheimer Disease

path(MESH:"Plaque, Amyloid") association a(MESH:Exosomes) View Subject | View Object

AD brain samples contain exosomal proteins within amyloid plaques hinting that exosomes play part in disease pathology (Rajendran et al., 2006) PubMed:28420982

Appears in Networks:
Annotations
Confidence
High
MeSH
Neocortex
MeSH
Alzheimer Disease

p(HGNC:MAPT) association act(a(MESH:Exosomes)) View Subject | View Object

Tau from the CSF (Saman et al., 2012) and blood of patients with AD (Fiandaca et al., 2015) is associated with exosomes PubMed:29238289

Appears in Networks:
Annotations
MeSH
Blood
MeSH
Cerebrospinal Fluid

Out-Edges 4

a(MESH:Exosomes) association p(HGNC:MAPT, pmod(Ph, Thr, 181)) View Subject | View Object

In support, tau associated with exosomes and phosphorylated at Thr-181 (AT270+ tau) has been identified in human CSF samples of AD patients PubMed:28420982

Appears in Networks:
Annotations
Confidence
High
MeSH
Cerebrospinal Fluid
MeSH
Alzheimer Disease

a(MESH:Exosomes) association sec(p(HGNC:MAPT)) View Subject | View Object

Recently, more evidence implies that the secretion of tau occurs through unconventional cellular pathways via vesicles known as exosomes (Saman et al., 2012) and ectosomes (Dujardin et al., 2014a) PubMed:28420982

Appears in Networks:
Annotations
Confidence
High
MeSH
Neocortex

a(MESH:Exosomes) association path(MESH:"Plaque, Amyloid") View Subject | View Object

AD brain samples contain exosomal proteins within amyloid plaques hinting that exosomes play part in disease pathology (Rajendran et al., 2006) PubMed:28420982

Appears in Networks:
Annotations
Confidence
High
MeSH
Neocortex
MeSH
Alzheimer Disease

act(a(MESH:Exosomes)) association p(HGNC:MAPT) View Subject | View Object

Tau from the CSF (Saman et al., 2012) and blood of patients with AD (Fiandaca et al., 2015) is associated with exosomes PubMed:29238289

Appears in Networks:
Annotations
MeSH
Blood
MeSH
Cerebrospinal Fluid

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.