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  3. complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55"))

complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55"))

Appears in Networks 1

Assembly and structure of protein phosphatase 2A v1.0.0

In-Edges 2

p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55") increases complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55")) View Subject | View Object

This analysis further suggests that the B subunit may form a relatively stable complex with the isolated scaffold subunit and does not seem to support the notion that the catalytic subunit is required for interaction between the scaffold and the B subunits PubMed:19277525

Appears in Networks:

act(p(HGNC:PPP2R1A)) increases complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55")) View Subject | View Object

First, conformational flexibility of the scaffold subunit is required for binding to the catalytic subunit and possibly other interacting proteins such as the regulatory subunits. PubMed:19277525

Appears in Networks:

Out-Edges 2

complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55")) hasComponent p(HGNC:PPP2R1A) View Subject | View Object

Appears in Networks:

complex(p(HGNC:PPP2R1A), p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55")) hasComponent p(INTERPRO:"Protein phosphatase 2A regulatory subunit PR55") View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.