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composite(a(CHEBI:chlorobutanol), p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)))

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Components

Appears in Networks 1

The autism/neuroprotection-linked ADNP/NAP regulate the excitatory glutamatergic synapse v1.0.0

In-Edges 0

Out-Edges 4

composite(a(CHEBI:chlorobutanol), p(HGNC:ADNP, pmod(MESH:Haploinsufficiency))) hasComponent a(CHEBI:chlorobutanol) View Subject | View Object

Appears in Networks:

composite(a(CHEBI:chlorobutanol), p(HGNC:ADNP, pmod(MESH:Haploinsufficiency))) hasComponent p(HGNC:ADNP, pmod(MESH:Haploinsufficiency)) View Subject | View Object

Appears in Networks:

composite(a(CHEBI:chlorobutanol), p(HGNC:ADNP, pmod(MESH:Haploinsufficiency))) decreases path(MESH:Smell) View Subject | View Object

Interestingly, in CB-treated males, Adnp haploinsufficiency showed a reduction in the total time spent with the different odors, which was significantly increased upon NAP treatment (Fig. 2e, inset). PubMed:30664622

Appears in Networks:
Annotations
Gender
Male

composite(a(CHEBI:chlorobutanol), p(HGNC:ADNP, pmod(MESH:Haploinsufficiency))) increases path(MESH:Smell) View Subject | View Object

As opposed to this, in females, CB-treated Adnp haploinsufficient mice showed significant increased total odor sniffing time, which was significantly reduced by NAP treatment (Supplemental Fig. S2E, inset). PubMed:30664622

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Annotations
Gender
Female

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.