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complex(a(GO:"plasma membrane"), p(HGNC:SLC5A7))

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Components

Appears in Networks 1

Alzheimer's Disease: Targeting the Cholinergic System v1.0.0

In-Edges 2

bp(GO:"action potential initiation") association complex(a(GO:"plasma membrane"), p(HGNC:SLC5A7)) View Subject | View Object

It is possible that the presence of CHT1 in the membrane of synaptic vesicles and the consequent increase in CHT1 relocation to the plasma membrane following neuronal depolarization could explain why an increase in neuronal firing promotes increased choline reuptake and, thus, ACh synthesis PubMed:26813123

Appears in Networks:
Annotations
MeSH
Neurons

bp(GO:"membrane depolarization") increases complex(a(GO:"plasma membrane"), p(HGNC:SLC5A7)) View Subject | View Object

It is possible that the presence of CHT1 in the membrane of synaptic vesicles and the consequent increase in CHT1 relocation to the plasma membrane following neuronal depolarization could explain why an increase in neuronal firing promotes increased choline reuptake and, thus, ACh synthesis PubMed:26813123

Appears in Networks:
Annotations
MeSH
Neurons

Out-Edges 3

complex(a(GO:"plasma membrane"), p(HGNC:SLC5A7)) hasComponent a(GO:"plasma membrane") View Subject | View Object

Appears in Networks:

complex(a(GO:"plasma membrane"), p(HGNC:SLC5A7)) hasComponent p(HGNC:SLC5A7) View Subject | View Object

Appears in Networks:

complex(a(GO:"plasma membrane"), p(HGNC:SLC5A7)) association bp(GO:"action potential initiation") View Subject | View Object

It is possible that the presence of CHT1 in the membrane of synaptic vesicles and the consequent increase in CHT1 relocation to the plasma membrane following neuronal depolarization could explain why an increase in neuronal firing promotes increased choline reuptake and, thus, ACh synthesis PubMed:26813123

Appears in Networks:
Annotations
MeSH
Neurons

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.