1. Catalog
  2. Nodes
  3. complex(a(CHEBI:hemin), p(HGNC:SERPINA1))

complex(a(CHEBI:hemin), p(HGNC:SERPINA1))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 0

Out-Edges 5

complex(a(CHEBI:hemin), p(HGNC:SERPINA1)) hasComponent a(CHEBI:hemin) View Subject | View Object

Appears in Networks:

complex(a(CHEBI:hemin), p(HGNC:SERPINA1)) hasComponent p(HGNC:SERPINA1) View Subject | View Object

Appears in Networks:

complex(a(CHEBI:hemin), p(HGNC:SERPINA1)) causesNoChange r(HGNC:TLR2) View Subject | View Object

Exposure of cells to hemin or hemin plus A1AT did not change TLR2/4 mRNA levels (Fig. 12). PubMed:28716864

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
Text Location
Results

complex(a(CHEBI:hemin), p(HGNC:SERPINA1)) causesNoChange r(HGNC:TLR4) View Subject | View Object

Exposure of cells to hemin or hemin plus A1AT did not change TLR2/4 mRNA levels (Fig. 12). PubMed:28716864

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
Text Location
Results

complex(a(CHEBI:hemin), p(HGNC:SERPINA1)) causesNoChange r(HGNC:LRP1) View Subject | View Object

Of note, hemin significantly lowered LRP1 mRNA, whereas hemin/A1AT had no significant effect on LRP1 expression relative to controls (Supplemental Fig. 2). PubMed:28716864

Appears in Networks:
Annotations
Cell Ontology (CL)
neutrophil
Text Location
Results

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.