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bp(GO:"heme catabolic process")

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Entity

Name
heme catabolic process
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

p(HGNC:HMOX1) positiveCorrelation bp(GO:"heme catabolic process") View Subject | View Object

Once inside the cells, heme is catabolized by HO enzymes, generating equimolar amounts of biliverdin, carbon monoxide (CO), and Fe (Tenhunen et al., 1968). PubMed:24904418

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p(HGNC:LRP1) increases bp(GO:"heme catabolic process") View Subject | View Object

Hx inhibits the oxidative property of heme (Eskew et al., 1999) and mediates heme transportation to intracellular compartments through the macrophage receptor CD91 (Hvidberg et al., 2005), a critical step on heme catabolism. PubMed:24904418

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Out-Edges 4

bp(GO:"heme catabolic process") positiveCorrelation p(HGNC:HMOX1) View Subject | View Object

Once inside the cells, heme is catabolized by HO enzymes, generating equimolar amounts of biliverdin, carbon monoxide (CO), and Fe (Tenhunen et al., 1968). PubMed:24904418

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Annotations
Text Location
Review

bp(GO:"heme catabolic process") increases a(MESH:Biliverdine) View Subject | View Object

Once inside the cells, heme is catabolized by HO enzymes, generating equimolar amounts of biliverdin, carbon monoxide (CO), and Fe (Tenhunen et al., 1968). PubMed:24904418

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Text Location
Review

bp(GO:"heme catabolic process") increases a(CHEBI:"carbon monoxide") View Subject | View Object

Once inside the cells, heme is catabolized by HO enzymes, generating equimolar amounts of biliverdin, carbon monoxide (CO), and Fe (Tenhunen et al., 1968). PubMed:24904418

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Text Location
Review

bp(GO:"heme catabolic process") increases a(CHEBI:"iron(2+)") View Subject | View Object

Once inside the cells, heme is catabolized by HO enzymes, generating equimolar amounts of biliverdin, carbon monoxide (CO), and Fe (Tenhunen et al., 1968). PubMed:24904418

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Text Location
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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.