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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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a(CHEBI:quinine) decreases complex(a(CHEBI:heme), p(MGI:Dock8)) View Subject | View Object

Notably, quinine diminished the association of heme with DOCK8 without affecting the association of heme with MPP1 or LGALS3 in RAW264.7 macrophages (Fig. 8d), suggesting that quinine exerted its protective effect by specifically disrupting the heme-DOCK8 association. PubMed:27798618

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Cell Ontology (CL)
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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.