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a(PUBCHEM:164676)

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Entity

Name
164676
Namespace
PUBCHEM
Namespace Version
None
Pattern
^\d+$

Appears in Networks 1

Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer’s disease v1.0.0

In-Edges 0

Out-Edges 12

a(PUBCHEM:164676) decreases act(p(HGNC:NOS2)) View Subject | View Object

It inhibited the activation of iNOS, matrix metalloproteinase 2 (MMP2), and NF-Bp65 and consequently prevent AD in the brain [229–231]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:164676) decreases act(p(HGNC:MMP2)) View Subject | View Object

It inhibited the activation of iNOS, matrix metalloproteinase 2 (MMP2), and NF-Bp65 and consequently prevent AD in the brain [229–231]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:164676) decreases act(p(HGNC:RELA)) View Subject | View Object

It inhibited the activation of iNOS, matrix metalloproteinase 2 (MMP2), and NF-Bp65 and consequently prevent AD in the brain [229–231]. PubMed:29179999

Appears in Networks:

a(PUBCHEM:164676) decreases path(MESH:"Alzheimer Disease") View Subject | View Object

It inhibited the activation of iNOS, matrix metalloproteinase 2 (MMP2), and NF-Bp65 and consequently prevent AD in the brain [229–231]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Brain

a(PUBCHEM:164676) decreases bp(GO:"apoptotic process") View Subject | View Object

Moreover, tanshinone IIA inhibited apoptosis in A 25-35-induced cells [232] and exerted anti-inflammatory activity in atherosclerosis and neuroprotective activity in cerebral ischemia/reperfusion impairment [233,234] PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(PUBCHEM:164676) decreases path(MESH:Inflammation) View Subject | View Object

Moreover, tanshinone IIA inhibited apoptosis in A 25-35-induced cells [232] and exerted anti-inflammatory activity in atherosclerosis and neuroprotective activity in cerebral ischemia/reperfusion impairment [233,234] PubMed:29179999

Appears in Networks:
Annotations
MeSH
Atherosclerosis

a(PUBCHEM:164676) decreases bp(GO:"neuron death") View Subject | View Object

Moreover, tanshinone IIA inhibited apoptosis in A 25-35-induced cells [232] and exerted anti-inflammatory activity in atherosclerosis and neuroprotective activity in cerebral ischemia/reperfusion impairment [233,234] PubMed:29179999

Appears in Networks:
Annotations
MeSH
Brain Ischemia

a(PUBCHEM:164676) decreases p(HGNC:GFAP) View Subject | View Object

Tanshinone IIA reduced the glial fibrillary acidic protein (GFAP) and NF-B and induced the expression of neuronal nuclear antigen (NeuN), Nissl bodies, and IB in AD [235,236]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(PUBCHEM:164676) decreases p(FPLX:NFkappaB) View Subject | View Object

Tanshinone IIA reduced the glial fibrillary acidic protein (GFAP) and NF-B and induced the expression of neuronal nuclear antigen (NeuN), Nissl bodies, and IB in AD [235,236]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(PUBCHEM:164676) increases p(HGNC:RBFOX3) View Subject | View Object

Tanshinone IIA reduced the glial fibrillary acidic protein (GFAP) and NF-B and induced the expression of neuronal nuclear antigen (NeuN), Nissl bodies, and IB in AD [235,236]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(PUBCHEM:164676) increases a(MESH:"Nissl Bodies") View Subject | View Object

Tanshinone IIA reduced the glial fibrillary acidic protein (GFAP) and NF-B and induced the expression of neuronal nuclear antigen (NeuN), Nissl bodies, and IB in AD [235,236]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

a(PUBCHEM:164676) increases p(FPLX:IKB) View Subject | View Object

Tanshinone IIA reduced the glial fibrillary acidic protein (GFAP) and NF-B and induced the expression of neuronal nuclear antigen (NeuN), Nissl bodies, and IB in AD [235,236]. PubMed:29179999

Appears in Networks:
Annotations
MeSH
Alzheimer Disease

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.