Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Appears in Networks 2

In-Edges 3

p(HBP:"Tau isoform F (441 aa)", var("p.Lys280del")) decreases act(a(GO:dendrite)) View Subject | View Object

By contrast, dendrites that do not contain Tau are richly decorated with spines (>1 spines per μm), indicating that there is only local impairment of dendritic function in case of proaggregant Tau missorting PubMed:27671637

p(HGNC:DISC1) association a(GO:dendrite) View Subject | View Object

This gene encodes for the DISC1 ubiquitous protein, which is implicated in neurogenesis, neuronal migration, axon/dendrite, and synapse formation PubMed:30061532

path(MESH:Schizophrenia) decreases a(GO:dendrite) View Subject | View Object

Notably, a marked reduction in MAP2 immunoreactivity, along with a decrease in dendritic arbor, is reported in the primary auditory cortex (BA41) of schizophrenic subjects compared with healthy controls PubMed:30061532

Out-Edges 1

a(GO:dendrite) association p(HGNC:DISC1) View Subject | View Object

This gene encodes for the DISC1 ubiquitous protein, which is implicated in neurogenesis, neuronal migration, axon/dendrite, and synapse formation PubMed:30061532

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.