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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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p(HGNC:HBB) increases rxn(reactants(a(CHEBI:"nitric oxide")), products(a(CHEBI:nitrate))) View Subject | View Object

Free Hb and Hb present in microvesicles oxidize vascular nitric oxide (NO) much faster than RBC-encapsulated Hb to form nitrate.14,15 PubMed:27308950

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p(HGNC:HBB) increases rxn(reactants(a(CHEBI:"nitric oxide")), products(a(CHEBI:nitrate))) View Subject | View Object

These data suggest that co-administration of human haptoglobin or hemopexin does 276 not attenuate the conversion of NO to nitrate that is mediated by cell-free murine 277 hemoglobin. PubMed:28314763

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.