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complex(p(HGNC:TFEB), p(INTERPRO:"cAMP response element binding (CREB) protein"))

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Components

Appears in Networks 1

Alzheimer’s disease and the autophagic-lysosomal system v1.0.0

In-Edges 2

bp(GO:"cellular response to stress") increases complex(p(HGNC:TFEB), p(INTERPRO:"cAMP response element binding (CREB) protein")) View Subject | View Object

Under starvation or stress, TFEB translocates to the nucleus and binds the CRE element to promote expression of macroautophagy and lysosomal genes [88]. PubMed:29758300

Appears in Networks:

path(MESH:Starvation) increases complex(p(HGNC:TFEB), p(INTERPRO:"cAMP response element binding (CREB) protein")) View Subject | View Object

Under starvation or stress, TFEB translocates to the nucleus and binds the CRE element to promote expression of macroautophagy and lysosomal genes [88]. PubMed:29758300

Appears in Networks:

Out-Edges 4

complex(p(HGNC:TFEB), p(INTERPRO:"cAMP response element binding (CREB) protein")) hasComponent p(HGNC:TFEB) View Subject | View Object

Appears in Networks:

complex(p(HGNC:TFEB), p(INTERPRO:"cAMP response element binding (CREB) protein")) hasComponent p(INTERPRO:"cAMP response element binding (CREB) protein") View Subject | View Object

Appears in Networks:

complex(p(HGNC:TFEB), p(INTERPRO:"cAMP response element binding (CREB) protein")) increases bp(GO:macroautophagy) View Subject | View Object

Under starvation or stress, TFEB translocates to the nucleus and binds the CRE element to promote expression of macroautophagy and lysosomal genes [88]. PubMed:29758300

Appears in Networks:

complex(p(HGNC:TFEB), p(INTERPRO:"cAMP response element binding (CREB) protein")) increases a(GO:lysosome) View Subject | View Object

Under starvation or stress, TFEB translocates to the nucleus and binds the CRE element to promote expression of macroautophagy and lysosomal genes [88]. PubMed:29758300

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.