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p(NCBIGENE:140621)

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Entity

Name
140621
Namespace
NCBIGENE
Namespace Version
None
Pattern
^\d+$

Appears in Networks 1

Corticotropin-releasing factor regulates caspase-3 and may protect developing zebrafish from stress-induced apoptosis v1.0.0

In-Edges 4

a(MESH:antalarmin) increases act(p(NCBIGENE:140621)) View Subject | View Object

However, embryos that recovered from heat shock in the presence of the CRF-R1 antagonist, antalarmin, experienced a greater increase in caspase-3 activity than embryos not given the antagonist PubMed:29807032

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
embryonic cell line

bp(MESH:"Heat-Shock Response") association act(p(NCBIGENE:140621)) View Subject | View Object

The endogenous response to heat shock was characterized by transient changes in caspase-3 activity and gene expression. PubMed:29807032

Appears in Networks:

bp(MESH:"Heat-Shock Response") increases act(p(NCBIGENE:140621)) View Subject | View Object

For embryos heat shocked at 6 hpf, the induction of caspase-3 activity was dependent on recovery time (interaction of main variables P=0.007), with a significant increase over controls at 7 h and 10 h recovery (Table 1). PubMed:29807032

Appears in Networks:

p(NCBIGENE:492507) decreases act(p(NCBIGENE:140621)) View Subject | View Object

CRF overexpression by mRNA microinjection reduced heat shock-induced caspase-3 activity by approximately 2-fold relative to control-injected embryos PubMed:29807032

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
embryonic cell line

Out-Edges 1

act(p(NCBIGENE:140621)) association bp(MESH:"Heat-Shock Response") View Subject | View Object

The endogenous response to heat shock was characterized by transient changes in caspase-3 activity and gene expression. PubMed:29807032

Appears in Networks:

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.