The node-based overlap between this network and other networks is calculated as the Szymkiewicz-Simpson coefficient of their respective nodes. Up to the top 10 are shown below.
|Tau Modifications v1.9.5||96%|
|Inert and seed-competent tau monomers suggest structural origins of aggregation v1.0.0||50%|
|Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation v1.0.0||36%|
|Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease v1.0.0||33%|
|Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways v1.0.1||26%|
|Alzheimer's disease pathological lesions activate the spleen tyrosine kinase. v1.0.0||24%|
|Tau in physiology and pathology v1.0.0||23%|
|Identification of the Tau phosphorylation pattern that drives its aggregation v1.0.0||23%|
|Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport. v1.0.0||20%|
|Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro v1.0.0||18%|
MB is a phenothiazine that crosses the blood brain barrier and acts as a redox cycler. Moreover, besides its beneficial properties as being able to improve energy metabolism and to act as an antioxidant, it is also able to reduce tau protein aggregation
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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.