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Choroid Plexus

Name
Choroid Plexus
Namespace Keyword
MeSHAnatomy
Namespace
MeSH
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/mesh-anatomy/mesh-anatomy-20170511.belanno

Sample Annotated Edges 5

p(HBP:"tau aggregates") association path(MESH:"Brain Injuries, Traumatic") View Subject | View Object

These findings support the link between TBI and tau aggre- gation, with resulting neurodegeneration similar to that seen in AD and chronic traumatic encephalopathy PubMed:26195256

Appears in Networks:
Annotations
MeSH
Choroid Plexus

p(HGNC:MAPT, pmod(Ph)) decreases act(p(MESH:Calpain)) View Subject | View Object

Phosphorylation of tau by protein kinase A increases its resistance to degradation by calpain PubMed:26195256

Appears in Networks:
Annotations
MeSH
Choroid Plexus

p(MESH:"Cyclic AMP-Dependent Protein Kinases") increases p(HGNC:MAPT, pmod(Ph)) View Subject | View Object

Phosphorylation of tau by protein kinase A increases its resistance to degradation by calpain PubMed:26195256

Appears in Networks:
Annotations
MeSH
Choroid Plexus

act(p(MESH:Calpain)) decreases p(HGNC:MAPT) View Subject | View Object

Phosphorylation of tau by protein kinase A increases its resistance to degradation by calpain PubMed:26195256

Appears in Networks:
Annotations
MeSH
Choroid Plexus

act(p(MESH:Lysosomes)) decreases p(HGNC:MAPT) View Subject | View Object

Tau is mainly cleared through intracellular degrada- tion by lysosomes via the autophagy–lysosome pathway, and by proteasomes via the ubiquitin–proteasome pathway.202 PubMed:26195256

Appears in Networks:
Annotations
MeSH
Choroid Plexus

Showing 5 of 9 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.