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glutamatergic neuron

Name
glutamatergic neuron
Namespace Keyword
Cell
Namespace
Cell Ontology (CL)
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/cell/cell-20170511.belanno

Sample Annotated Edges 5

sec(a(CHEBI:"glutamate(2-)")) increases bp(GO:"long-term synaptic potentiation") View Subject | View Object

The combination of enhanced glutamatergic release and strong postsynaptic response produces LTP of the glutamatergic afferents. PubMed:17009926

Appears in Networks:
Annotations
Cell Ontology (CL)
glutamatergic neuron

bp(GO:"depolarization of postsynaptic membrane") increases bp(GO:"long-term synaptic potentiation") View Subject | View Object

The combination of enhanced glutamatergic release and strong postsynaptic response produces LTP of the glutamatergic afferents. PubMed:17009926

Appears in Networks:
Annotations
Cell Ontology (CL)
glutamatergic neuron

bp(GO:"regulation of synaptic plasticity") association p(FPLX:CHRN) View Subject | View Object

Nicotinic receptors also modulate glutamatergic synaptic plasticity. PubMed:17009926

Appears in Networks:
Annotations
Cell Ontology (CL)
glutamatergic neuron

p(FPLX:CHRN) association bp(GO:"regulation of synaptic plasticity") View Subject | View Object

Nicotinic receptors also modulate glutamatergic synaptic plasticity. PubMed:17009926

Appears in Networks:
Annotations
Cell Ontology (CL)
glutamatergic neuron

act(p(MESH:"Receptors, N-Methyl-D-Aspartate")) increases bp(GO:"long-term synaptic potentiation") View Subject | View Object

This depolarization and firing of the DA neurons helps to relieve the divalent cation block of NMDA receptors and, thus, enables the NMDA receptors to participate in long-term synaptic potentiation of glutamatergic afferents onto midbrain dopamine neurons. PubMed:26472524

Appears in Networks:
Annotations
Cell Ontology (CL)
glutamatergic neuron

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About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.