1. Catalog
  2. Namespaces
  3. Uberon
  4. blood plasma

blood plasma

Name
blood plasma
Namespace Keyword
Anatomy
Namespace
Uberon
Namespace Version
20170511
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/annotation/anatomy/anatomy-20170511.belanno

Sample Annotated Edges 5

act(a(CHEBI:"L-dopa")) negativeCorrelation a(CHEBI:"folate(2-)") View Subject | View Object

Here, we found that administration of L-dopa led to a significant 5-fold increase in plasma tHcy concentrations, when compared to saline treated mice (Table 1). This L-dopa induced increase in plasma tHcy was significantly greater in mice that had been reared on either low folate (LF) or FD diets (Table 1). PubMed:22764226

Appears in Networks:
Annotations
Uberon
blood plasma

act(a(CHEBI:"L-dopa")) increases a(CHEBI:homocysteine) View Subject | View Object

Here, we found that administration of L-dopa led to a significant 5-fold increase in plasma tHcy concentrations, when compared to saline treated mice (Table 1). This L-dopa induced increase in plasma tHcy was significantly greater in mice that had been reared on either low folate (LF) or FD diets (Table 1). PubMed:22764226

Appears in Networks:
Annotations
Uberon
blood plasma

act(a(CHEBI:"L-dopa")) decreases p(MGI:Ppp2ca, pmod(Me)) View Subject | View Object

Reductions in PP2A methylation were associated with a concomitant increase in each brain region of p-Tau at the PHF-1 epitope (Fig. 6A,B). PubMed:22764226

Appears in Networks:
Annotations
Uberon
blood plasma

a(CHEBI:"folate(2-)") negativeCorrelation act(a(CHEBI:"L-dopa")) View Subject | View Object

Here, we found that administration of L-dopa led to a significant 5-fold increase in plasma tHcy concentrations, when compared to saline treated mice (Table 1). This L-dopa induced increase in plasma tHcy was significantly greater in mice that had been reared on either low folate (LF) or FD diets (Table 1). PubMed:22764226

Appears in Networks:
Annotations
Uberon
blood plasma

a(CHEBI:homocysteine) biomarkerFor path(MESH:"Alzheimer Disease") View Subject | View Object

Receiver-operating characteristic curves and logistic regression analyses showed that combined assessment of DYRK1A, BDNF and homocysteine has a sensitivity of 0.952, a specificity of 0.889 and an accuracy of 0.933 in testing for AD. The blood levels of these markers provide a diagnosis assessment profile. Combined assessment of these three markers outperforms most of the previous markers and could become a useful substitute to the current panel of AD biomarkers. PubMed:28632203

Appears in Networks:
Annotations
Uberon
blood plasma
MeSH
Alzheimer Disease

Showing 5 of 14 edges

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.