composite(complex(GO:"filamentous actin"), p(HGNC:CFL1)) decreases complex(GO:"filamentous actin")

PubMed:29215007

One of these binding partners is cofilin, a 21 kDa eukaryotic protein, which binds to F-actin with a Kd < 0.05 μM33 and results in disassembly of F-actin34, 35. Cryo-electron microscopy further showed that the binding site of cofilin on F-actin is highly similar to its binding site on G-actin (Fig. 2a)32

Confidence

Medium

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.