p(HGNC:MTOR) decreases bp(GO:autophagy)

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PubMed:30061532

The biological implication behind an impairment of microtubule dynamics is confirmed in post-mortem schizophrenic brain samples, as well as in mouse models of schizophrenia, where mTOR-dependent autophagy dysfunction is accompanied by an altered gene expression and protein levels of the microtubule-associated protein 6 (MAP6)

Related Edges 4

• act(a(GO:microtubule)) negativeCorrelation path(MESH:Schizophrenia)
• p(HGNC:MAP6) association act(p(HGNC:MTOR))
• act(p(HGNC:MTOR)) association p(HGNC:MAP6)
• path(MESH:Schizophrenia) negativeCorrelation act(a(GO:microtubule))

MeSH

Brain

MeSH

Schizophrenia

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