act(p(HGNC:CAMK2A)) increases act(complex(GO:"NF-kappaB complex"))

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PubMed:28745240

The three well characterized sensors of intracellular calcium – calmodulin/CamKII pathway, PI3K/ Akt pathway, and protein kinase C (PKC) pathway – are known to induce NF-κB activation and couple upstream signal transduction pathways that induce calcium dyshomeostasis to NF-κB activation

Related Edges 3

• bp(HBP:"PI3K-Akt signaling pathway") increases act(complex(GO:"NF-kappaB complex"))
• act(complex(GO:"NF-kappaB complex")) decreases bp(GO:"calcium ion homeostasis")
• act(p(FPLX:PKC)) increases act(complex(GO:"NF-kappaB complex"))

MeSH

Alzheimer Disease

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