a(CHEBI:heme) increases path(MESH:Inflammation)

View Subject View Object

PubMed:28314763

Increased plasma concentrations of cell-free heme, the breakdown product of 390 hemoglobin, promote activation and inflammation of endothelial cells and enhance 391 oxidative stress and vascular permeability (22).

Related Edges 2

• a(CHEBI:heme) increases bp(GO:"endothelial cell activation")
• a(CHEBI:heme) increases bp(MESH:"Oxidative Stress")

Cell Ontology (CL)

endothelial cell

MeSH

Arteries

MeSH

Diabetes Mellitus

Text Location

Introduction

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.

---