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a(CHEBI:oxysterol)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
oxysterol
Namespace
chebi
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/chebi-names.belns

Appears in Networks 2

Nuclear receptors as therapeutic targets for Alzheimer's disease. v1.0.0

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

bp(HM:"Atheromatous lesions") positiveCorrelation a(CHEBI:oxysterol) View Subject | View Object

Oxysterols and oxidation products of polyunsaturated fatty acids (PUFAs) are present in human atheromatous lesions.4,5 PubMed:20378845

Appears in Networks:

Out-Edges 3

a(CHEBI:oxysterol) increases act(p(HGNC:NR1H3)) View Subject | View Object

LXR receptors are activated by oxysterols, most prominently hydroxylated forms of cholesterol, and play a critical role in the control of whole body cholesterol homeostasis, as well as exerting potent anti-inflammatory actions [26]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
High
MeSH
Microglia

a(CHEBI:oxysterol) increases act(p(HGNC:NR1H3)) View Subject | View Object

LXR receptors are activated by oxysterols, most prominently hydroxylated forms of cholesterol, and play a critical role in the control of whole body cholesterol homeostasis, as well as exerting potent anti-inflammatory actions [26]. PubMed:21718217

Appears in Networks:
Annotations
Confidence
Medium

a(CHEBI:oxysterol) positiveCorrelation bp(HM:"Atheromatous lesions") View Subject | View Object

Oxysterols and oxidation products of polyunsaturated fatty acids (PUFAs) are present in human atheromatous lesions.4,5 PubMed:20378845

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.