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path(HP:"Elevated mean arterial pressure")

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Entity

Name
Elevated mean arterial pressure
Namespace
HP
Namespace Version
2017-10-05
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/namespace/hp/hp-20171108.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 2

p(HGNC:HBB) negativeCorrelation path(HP:"Elevated mean arterial pressure") View Subject | View Object

Children undergoing open heart surgery experience a progressively increasing risk of postoperative infection and thrombosis, increasing need for mechanical ventilation and inotropes, increasing Day 1 through Day 2 peak blood lactate, and decreased nadir mean arterial pressure as the levels of free Hb increase and the levels of haptoglobin decrease. PubMed:29603246

Appears in Networks:
Annotations
MeSH
Blood
MeSH
Anemia, Sickle Cell
Text Location
Discussion

p(HGNC:HP) negativeCorrelation path(HP:"Elevated mean arterial pressure") View Subject | View Object

Preoperative adult normal haptoglobin levels, compared with lower preoperative haptoglobin levels, were associated with significantly lower Day 1 peak blood lactate levels and higher nadir mean arterial pressures on day one (Figs. S1 and S2, available as supporting information in the online version of this paper) as well as on the first and second days postoperatively (data not shown). PubMed:29603246

Appears in Networks:
Annotations
MeSH
Blood
MeSH
Anemia, Sickle Cell
Text Location
Results

Out-Edges 2

path(HP:"Elevated mean arterial pressure") negativeCorrelation p(HGNC:HP) View Subject | View Object

Preoperative adult normal haptoglobin levels, compared with lower preoperative haptoglobin levels, were associated with significantly lower Day 1 peak blood lactate levels and higher nadir mean arterial pressures on day one (Figs. S1 and S2, available as supporting information in the online version of this paper) as well as on the first and second days postoperatively (data not shown). PubMed:29603246

Appears in Networks:
Annotations
MeSH
Blood
MeSH
Anemia, Sickle Cell
Text Location
Results

path(HP:"Elevated mean arterial pressure") negativeCorrelation p(HGNC:HBB) View Subject | View Object

Children undergoing open heart surgery experience a progressively increasing risk of postoperative infection and thrombosis, increasing need for mechanical ventilation and inotropes, increasing Day 1 through Day 2 peak blood lactate, and decreased nadir mean arterial pressure as the levels of free Hb increase and the levels of haptoglobin decrease. PubMed:29603246

Appears in Networks:
Annotations
MeSH
Blood
MeSH
Anemia, Sickle Cell
Text Location
Discussion

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.