1. Catalog
  2. Nodes
  3. complex(a(CHEBI:epibatidine), a(MESH:"nicotinic receptor alpha3beta2"))

complex(a(CHEBI:epibatidine), a(MESH:"nicotinic receptor alpha3beta2"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

NACHO Mediates Nicotinic Acetylcholine Receptor Function throughout the Brain v1.0.0

In-Edges 2

p(HGNC:RIC3) causesNoChange complex(a(CHEBI:epibatidine), a(MESH:"nicotinic receptor alpha3beta2")) View Subject | View Object

For alpha7 and alpha3beta2, RIC-3 did not enable detectable [3H]epibatidine binding, yet RIC-3 profoundly augmented the effects of NACHO on [3H]epibatidine binding to either receptor subtype (Figures 3A and S1A) PubMed:28445721

Appears in Networks:

act(p(HGNC:TMEM35A), ma(chap)) increases complex(a(CHEBI:epibatidine), a(MESH:"nicotinic receptor alpha3beta2")) View Subject | View Object

Similarly, quantifiable [3H]epibatidine binding to alpha3beta2 required cotransfection with NACHO (Figure 2C) PubMed:28445721

Appears in Networks:

Out-Edges 2

complex(a(CHEBI:epibatidine), a(MESH:"nicotinic receptor alpha3beta2")) hasComponent a(CHEBI:epibatidine) View Subject | View Object

Appears in Networks:

complex(a(CHEBI:epibatidine), a(MESH:"nicotinic receptor alpha3beta2")) hasComponent a(MESH:"nicotinic receptor alpha3beta2") View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.