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Entity

Name
cell differentiation
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 3

In-Edges 3

p(MESH:"Receptors, Nicotinic") association bp(GO:"cell differentiation") View Subject | View Object

nAChRs are expressed also at the somatodendritic postsynaptic site, where they regulate neuron depolarisation, firing and long- term potentiation [9]. Moreover these receptors are also in- volved in proliferation, differentiation and migration of neu- ral progenitors PubMed:28901280

bp(GO:"ubiquitin-dependent protein catabolic process") regulates bp(GO:"cell differentiation") View Subject | View Object

Ubiquitin-mediated proteolysis of a variety of cellular proteins plays an important role in many basic cellular processes. Among these are regulation of cell cycle and division, differentiation and development, involvement in the cellular response to stress and extracellular effectors, morphogenesis of neuronal networks, modulation of cell surface receptors, ion channels and the secretory pathway, DNA repair, transcriptional regulation, transcriptional silencing, long-term memory, circadian rhythms, regulation of the immune and inflammatory responses,and biogenesis of organelles PubMed:14556719

a(CHEBI:"reactive oxygen species") regulates bp(GO:"cell differentiation") View Subject | View Object

Specifically, ROS have been shown to regulate a wide variety of signalling pathways including anti- inflammatory responses and adaptation to hypoxia [77,78], autop- hagy [79], immune cell function [80], cellular differentiation [81], integrins [82], as well as oncogenes signalling [83]. PubMed:24563850

Out-Edges 1

bp(GO:"cell differentiation") association p(MESH:"Receptors, Nicotinic") View Subject | View Object

nAChRs are expressed also at the somatodendritic postsynaptic site, where they regulate neuron depolarisation, firing and long- term potentiation [9]. Moreover these receptors are also in- volved in proliferation, differentiation and migration of neu- ral progenitors PubMed:28901280

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.