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path(MESH:Smoking)

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Entity

Name
Smoking
Namespace
mesh
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/mesh-names.belns

Appears in Networks 4

Amyloid β oligomers (AβOs) in Alzheimer’s disease v1.0.0

Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses v1.0.0

Anatabine ameliorates experimental autoimmune thyroiditis. v1.0.0

Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons v1.0.0

In-Edges 4

p(HGNC:TPO) negativeCorrelation path(MESH:Smoking) View Subject | View Object

Smokers in the Third National Health and Nutri- tion Examination Survey were found to have lower prev- alence of thyroperoxidase and/or thyroglobulin antibod- ies than nonsmokers (1). PubMed:22807490

Appears in Networks:

path(MESH:"Colitis, Ulcerative") association path(MESH:Smoking) View Subject | View Object

Tobacco smoking has numerous detrimental effects on human health, but it has also been associated with a few apparent salutary actions, including the amelioration of autoimmune (Hashimoto) thyroiditis and ulcerative colitis. PubMed:22807490

Appears in Networks:

path(MESH:"Hashimoto Disease") association path(MESH:Smoking) View Subject | View Object

Tobacco smoking has numerous detrimental effects on human health, but it has also been associated with a few apparent salutary actions, including the amelioration of autoimmune (Hashimoto) thyroiditis and ulcerative colitis. PubMed:22807490

Appears in Networks:

a(CHEBI:Mecamylamine) decreases path(MESH:Smoking) View Subject | View Object

Also, mecamylamine is sometimes used as an anti-addictive drug to help people stop smoking tobacco products (e.g.,[128, 129]) PubMed:28391535

Appears in Networks:

Out-Edges 6

path(MESH:Smoking) increases path(MESH:"Alzheimer Disease") View Subject | View Object

The risk factors of AD include: increasing age, vascular factors such as smoking, obesity, and diabetes (Reitz and Mayeux 2014) as well as genetic mutations. PubMed:29196815

Appears in Networks:
Annotations
Confidence
High

path(MESH:Smoking) decreases path(MESH:"Parkinson Disease") View Subject | View Object

However, when all genetic factors are eliminated by studying monozygotic twins who are discordant for both tobacco use and Parkinson’s disease, tobacco smoking and chewing still decrease the risk of Parkinson’s disease (Tanner et al., 2002; Wirdefeldt et al., 2005) PubMed:21482353

Appears in Networks:

path(MESH:Smoking) association path(MESH:"Hashimoto Disease") View Subject | View Object

Tobacco smoking has numerous detrimental effects on human health, but it has also been associated with a few apparent salutary actions, including the amelioration of autoimmune (Hashimoto) thyroiditis and ulcerative colitis. PubMed:22807490

Appears in Networks:

path(MESH:Smoking) association path(MESH:"Colitis, Ulcerative") View Subject | View Object

Tobacco smoking has numerous detrimental effects on human health, but it has also been associated with a few apparent salutary actions, including the amelioration of autoimmune (Hashimoto) thyroiditis and ulcerative colitis. PubMed:22807490

Appears in Networks:

path(MESH:Smoking) negativeCorrelation p(HGNC:TPO) View Subject | View Object

Smokers in the Third National Health and Nutri- tion Examination Survey were found to have lower prev- alence of thyroperoxidase and/or thyroglobulin antibod- ies than nonsmokers (1). PubMed:22807490

Appears in Networks:

path(MESH:Smoking) increases a(MESH:"Blood Glucose") View Subject | View Object

Nicotine also suppresses insulin output from the pancreas, which indicates that smokers are usually hyperglycemic (higher blood sugar level) PubMed:28391535

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.