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  3. complex(a(GO:"NF-kappaB complex"), p(HGNC:NFKB1), p(HGNC:RELA))

complex(a(GO:"NF-kappaB complex"), p(HGNC:NFKB1), p(HGNC:RELA))

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Components

Appears in Networks 1

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis v1.0.0

In-Edges 0

Out-Edges 4

complex(a(GO:"NF-kappaB complex"), p(HGNC:NFKB1), p(HGNC:RELA)) hasComponent a(GO:"NF-kappaB complex") View Subject | View Object

Appears in Networks:

complex(a(GO:"NF-kappaB complex"), p(HGNC:NFKB1), p(HGNC:RELA)) hasComponent p(HGNC:NFKB1) View Subject | View Object

Appears in Networks:

complex(a(GO:"NF-kappaB complex"), p(HGNC:NFKB1), p(HGNC:RELA)) hasComponent p(HGNC:RELA) View Subject | View Object

Appears in Networks:

complex(a(GO:"NF-kappaB complex"), p(HGNC:NFKB1), p(HGNC:RELA)) increases act(complex(GO:"NF-kappaB p50/p65 complex")) View Subject | View Object

The constitutive form is transcriptionally active as evidenced by the nuclear localization of the p50 and p65 subunits in the neurons of the cortex and hippocampus PubMed:25652642

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Annotations
MeSH
Cerebral Cortex
MeSH
Hippocampus

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.