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path(MESH:"Retinal Degeneration")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Retinal Degeneration
Namespace
mesh
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/mesh-names.belns

Appears in Networks 1

Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β. v1.0.0

In-Edges 3

p(HGNC:AK1) increases path(MESH:"Retinal Degeneration") View Subject | View Object

Co-expression of an AK1 transgene with tau in flies (gl-tau2.1/UAS-AK1) markedly enhanced tau-induced retinal degeneration,indicating that AK1 enhances tau toxicity in the fly retina. PubMed:22419736

Appears in Networks:

p(HGNC:AK1) increases path(MESH:"Retinal Degeneration") View Subject | View Object

These results indicate that AK1 exacerbates rough eye phenotype and tau hyperpho- sphorylation in a tauopathy model organism and that there is a close correlation between the exacerbated rough eye pheno- type and tau phosphorylation. PubMed:22419736

Appears in Networks:

p(HGNC:MAPT, pmod(Ph)) association path(MESH:"Retinal Degeneration") View Subject | View Object

These results indicate that AK1 exacerbates rough eye phenotype and tau hyperpho- sphorylation in a tauopathy model organism and that there is a close correlation between the exacerbated rough eye pheno- type and tau phosphorylation. PubMed:22419736

Appears in Networks:

Out-Edges 1

path(MESH:"Retinal Degeneration") association p(HGNC:MAPT, pmod(Ph)) View Subject | View Object

These results indicate that AK1 exacerbates rough eye phenotype and tau hyperpho- sphorylation in a tauopathy model organism and that there is a close correlation between the exacerbated rough eye pheno- type and tau phosphorylation. PubMed:22419736

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.