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Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 1

a(CHEBI:"nitric oxide") decreases act(complex(p(HGNC:F13A1), p(HGNC:F13B))) View Subject | View Object

Finally, NO may also affect coagulation by inhibiting Factor XIII activity (Catani et al, 1998). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
Anemia, Hemolytic, Autoimmune
Text Location
Review

Out-Edges 4

complex(p(HGNC:F13A1), p(HGNC:F13B)) increases bp(HM:"fibrin monomer cross-linking") View Subject | View Object

Factor XIII stabilizes clots by catalysing fibrin monomer cross-linking; thus, NO deficiency enhances clot stability and reduces clot dissolution. PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
Anemia, Hemolytic, Autoimmune
Text Location
Review

complex(p(HGNC:F13A1), p(HGNC:F13B)) decreases path(MESH:"Clot Retraction") View Subject | View Object

Factor XIII stabilizes clots by catalysing fibrin monomer cross-linking; thus, NO deficiency enhances clot stability and reduces clot dissolution. PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
Anemia, Hemolytic, Autoimmune
Text Location
Review

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.