1. Catalog
  2. Nodes
  3. complex(p(HGNC:ESR1), p(HGNC:MAPT))

complex(p(HGNC:ESR1), p(HGNC:MAPT))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Components

Appears in Networks 1

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer's disease v1.0.0

In-Edges 1

path(MESH:"Alzheimer Disease") increases complex(p(HGNC:ESR1), p(HGNC:MAPT)) View Subject | View Object

Moreover, more ERα was found in the tau-5 immunoprecipitates from AD brain than control brain (p < 0.05) (Fig. 5B,C), demonstrating increased interaction between tau and ERα in the AD brain which is likely the mechanism that underlies increased sequestration of ERα by the PHFs in NFTs. PubMed:26837465

Appears in Networks:
Annotations
Confidence
High
MeSH
Cerebral Cortex
MeSH
Hippocampus

Out-Edges 2

complex(p(HGNC:ESR1), p(HGNC:MAPT)) hasComponent p(HGNC:ESR1) View Subject | View Object

Appears in Networks:

complex(p(HGNC:ESR1), p(HGNC:MAPT)) hasComponent p(HGNC:MAPT) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.