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complex(p(HGNC:HSP90AB1), p(HGNC:UNC45A))

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Components

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A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways v1.0.0

In-Edges 1

p(HGNC:UNC45A) directlyIncreases complex(p(HGNC:HSP90AB1), p(HGNC:UNC45A)) View Subject | View Object

The Hsp90 cochaperone UNC45A, but not its homolog UNC45B, were previously described as an Hsp90beta-specific cochaperone (Chadli et al., 2008) and this held true in our assay. We detected a similar preference for sFKBP38 (Figure 5D) PubMed:25036637

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Out-Edges 2

complex(p(HGNC:HSP90AB1), p(HGNC:UNC45A)) hasComponent p(HGNC:HSP90AB1) View Subject | View Object

Appears in Networks:

complex(p(HGNC:HSP90AB1), p(HGNC:UNC45A)) hasComponent p(HGNC:UNC45A) View Subject | View Object

Appears in Networks:

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BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.