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p(HGNC:PPP2CA, pmod(Ub))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
PPP2CA
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Protein phosphatase 2A dysfunction in Alzheimer’s disease v1.0.0

In-Edges 1

p(HGNC:PPP2CA) hasVariant p(HGNC:PPP2CA, pmod(Ub)) View Subject | View Object

Appears in Networks:

Out-Edges 1

p(HGNC:PPP2CA, pmod(Ub)) increases deg(complex(GO:"protein phosphatase type 2A complex")) View Subject | View Object

Other modifications of PP2AC subunit include ubiquitination, which targets PP2A for degradation (McConnelletal.,2010), and tyrosine nitration that increases PP2A activity in endothelial cells (Wu and Wilson, 2009). PubMed:24653673

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.