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p(HGNC:ATP13A2, var("?"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
ATP13A2
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection v1.0.0

In-Edges 1

p(HGNC:ATP13A2) hasVariant p(HGNC:ATP13A2, var("?")) View Subject | View Object

Appears in Networks:

Out-Edges 2

p(HGNC:ATP13A2, var("?")) increases bp(GO:"proteasomal protein catabolic process") View Subject | View Object

Diseasecausing mutations in ATP13A2 result in protein retention in the endoplasmic reticulum and enhanced proteasomal degradation, suggesting that neurodegeneration could be caused by overwhelming the UPS and/or loss of function in lysosomal protein degradation [39]. PubMed:18930136

Appears in Networks:

p(HGNC:ATP13A2, var("?")) increases path(HBP:Neurodegeneration) View Subject | View Object

Diseasecausing mutations in ATP13A2 result in protein retention in the endoplasmic reticulum and enhanced proteasomal degradation, suggesting that neurodegeneration could be caused by overwhelming the UPS and/or loss of function in lysosomal protein degradation [39]. PubMed:18930136

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.