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a(CHEBI:Hexamethonium)

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Entity

Name
Hexamethonium
Namespace
chebi
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/chebi-names.belns

Appears in Networks 1

Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons v1.0.0

In-Edges 1

act(a(CHEBI:nicotine)) negativeCorrelation a(CHEBI:Hexamethonium) View Subject | View Object

. It should be noted that hexamethonium, at relatively low doses, does not block the stimulus effects of (-)-nicotine but when administered at high doses has occasionally been reported to attenuate nicotine-like responding; probably the result of penetration into the CNS of a small proportion of the administered dose of drug (e.g., [35, 38, 64, 106, 146]) PubMed:28391535

Appears in Networks:

Out-Edges 1

a(CHEBI:Hexamethonium) negativeCorrelation act(a(CHEBI:nicotine)) View Subject | View Object

. It should be noted that hexamethonium, at relatively low doses, does not block the stimulus effects of (-)-nicotine but when administered at high doses has occasionally been reported to attenuate nicotine-like responding; probably the result of penetration into the CNS of a small proportion of the administered dose of drug (e.g., [35, 38, 64, 106, 146]) PubMed:28391535

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.