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complex(SCOMP:"PP2A Complex")

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Entity

Name
PP2A Complex
Namespace
SCOMP
Namespace Version
20170725
Namespace URL
https://arty.scai.fraunhofer.de/artifactory/bel/namespace/selventa-named-complexes/selventa-named-complexes-20170725.belns

Appears in Networks 1

TAU and Interaction Partners v1.2.5

TAU Interactions Section of NESTOR

In-Edges 3

act(complex(GO:microtubule)) directlyDecreases act(complex(SCOMP:"PP2A Complex")) View Subject | View Object

Thus, MTs inhibited the rate of tau dephosphorylation by ABaC. PubMed:10464280

Appears in Networks:

p(HGNC:PPP2CA) isA complex(SCOMP:"PP2A Complex") View Subject | View Object

Appears in Networks:

p(HBP:"microtubule-binding region") association act(complex(SCOMP:"PP2A Complex")) View Subject | View Object

Using tau deletion mutants, we found that ABaC binds a domain on tau that is indistinguishable from its MT-binding domain. PubMed:10464280

Appears in Networks:

Out-Edges 2

act(complex(SCOMP:"PP2A Complex")) association p(HBP:"microtubule-binding region") View Subject | View Object

Using tau deletion mutants, we found that ABaC binds a domain on tau that is indistinguishable from its MT-binding domain. PubMed:10464280

Appears in Networks:

act(complex(SCOMP:"PP2A Complex")) increases rxn(reactants(p(HGNC:MAPT, pmod(Ph))), products(a(CHEBI:"phosphate(3-)"), p(HGNC:MAPT))) View Subject | View Object

Thus, MTs inhibited the rate of tau dephosphorylation by ABaC. PubMed:10464280

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.