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p(HGNC:SLC2A1)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
SLC2A1
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Clearance of Amyloid Beta and Tau in Alzheimer’s Disease:from Mechanisms to Therapy v1.0.1

In-Edges 0

Out-Edges 5

p(HGNC:SLC2A1) increases p(HGNC:LRP1) View Subject | View Object

GLUT1, glucose transporter expressed in the BBB, regulates LRP1-dependent Aβ clearance via increasing the expression of LRP1 PubMed:29626319

Appears in Networks:
Annotations
MeSH
Blood-Brain Barrier

p(HGNC:SLC2A1) regulates deg(a(CHEBI:"amyloid-beta")) View Subject | View Object

GLUT1, glucose transporter expressed in the BBB, regulates LRP1-dependent Aβ clearance via increasing the expression of LRP1 PubMed:29626319

Appears in Networks:
Annotations
MeSH
Blood-Brain Barrier

p(HGNC:SLC2A1) regulates tloc(a(CHEBI:"amyloid-beta"), fromLoc(MESH:Brain), toLoc(MESH:Blood)) View Subject | View Object

In addition, the transport of GLUT1-mediated glucose into the brain is also beneficial to maintaining the integrity of the BBB, thereby ensuring the normal transport of Aβ from brain into blood (Winkler et al. 2015) PubMed:29626319

Appears in Networks:

p(HGNC:SLC2A1) regulates tloc(a(CHEBI:glucose), fromLoc(GO:"extracellular region"), toLoc(MESH:"Blood-Brain Barrier")) View Subject | View Object

In addition, the transport of GLUT1-mediated glucose into the brain is also beneficial to maintaining the integrity of the BBB, thereby ensuring the normal transport of Aβ from brain into blood (Winkler et al. 2015) PubMed:29626319

Appears in Networks:

p(HGNC:SLC2A1) regulates a(MESH:"Blood-Brain Barrier") View Subject | View Object

In addition, the transport of GLUT1-mediated glucose into the brain is also beneficial to maintaining the integrity of the BBB, thereby ensuring the normal transport of Aβ from brain into blood (Winkler et al. 2015) PubMed:29626319

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.