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bp(GO:"circadian sleep/wake cycle, REM sleep")

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Entity

Name
circadian sleep/wake cycle, REM sleep
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 2

Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous System v1.0.0

Alzheimer's Disease: Targeting the Cholinergic System v1.0.0

In-Edges 2

act(p(FPLX:CHRN)) increases bp(GO:"circadian sleep/wake cycle, REM sleep") View Subject | View Object

Moreover, although nicotine increases wakefulness in wild-type mice, it does not affect β2−/− mice. Overall, stimulation of nAChRs promotes arousal and REM sleep. PubMed:17009926

Appears in Networks:
Annotations
MeSH
Epilepsy

a(MESH:"Cholinergic Neurons") increases bp(GO:"circadian sleep/wake cycle, REM sleep") View Subject | View Object

It has been demonstrated that stimulation of cholinergic neurons in precise regions of the brainstem can promote REM (rapid eye movement) sleep, dose-dependently PubMed:26813123

Appears in Networks:
Annotations
MeSH
Brain Stem

Out-Edges 0

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.