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r(RGD:Ntrk2)

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Entity

Name
Ntrk2
Namespace
rgd
Namespace Version
20181021
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/f2f993e599694ab5ce989cc39d789a499f75db99/external/rgd-names.belns

Appears in Networks 1

The CRF1 receptor antagonist, antalarmin, reverses isolation-induced up-regulation of dopamine D2 receptors in the amygdala and nucleus accumbens of fawn-hooded rats v1.0.0

In-Edges 4

a(MESH:antalarmin) decreases r(RGD:Ntrk2) View Subject | View Object

Interestingly however, antalarmin treatment of GH rats caused a down-regulation of TrkB mRNA in the LC ()15%, P 1⁄4 0.012) and Pir ()26%, P 1⁄4 0.013) whilst increases were observed in the hippocampus (CA1–3; +36%, P 1⁄4 0.042) and RSc (+53%, P < 0.001). PubMed:16820021

Appears in Networks:
Annotations
MeSH
Piriform Cortex

a(MESH:antalarmin) increases r(RGD:Ntrk2) View Subject | View Object

Interestingly however, antalarmin treatment of GH rats caused a down-regulation of TrkB mRNA in the LC ()15%, P 1⁄4 0.012) and Pir ()26%, P 1⁄4 0.013) whilst increases were observed in the hippocampus (CA1–3; +36%, P 1⁄4 0.042) and RSc (+53%, P < 0.001). PubMed:16820021

Appears in Networks:
Annotations
MeSH
Hippocampus

path(HBP:"isolation rearing") decreases r(RGD:Ntrk2) View Subject | View Object

ISO resulted in a decrease in TrkB mRNA expression in the cingulate cortex (Cg1–3; F1,124 1⁄4 7.582, P 1⁄4 0.014) and piriform cortex (Pir; F1,119 1⁄4 3.869 PubMed:16820021

Appears in Networks:
Annotations
MeSH
Gyrus Cinguli
MeSH
Piriform Cortex

path(HBP:"isolation rearing") increases r(RGD:Ntrk2) View Subject | View Object

whereas an increase was observed in isolates compared to GH in the hippocampus (+38%; F1,59 1⁄4 14.131, P < 0.001), DG (+32%; F1,56 1⁄4 8.398, P 1⁄4 0.005) and RSc (+32%; F1,56 1⁄4 6.830, P 1⁄4 0.011). PubMed:16820021

Appears in Networks:
Annotations
MeSH
Dentate Gyrus
MeSH
Hippocampus

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.