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complex(a(GO:"filamentous actin"), p(HGNC:MAPT, frag("254_284")))

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Components

Appears in Networks 1

Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau v1.0.0

In-Edges 1

p(HGNC:MAPT, pmod(Ph, Ser, 262)) decreases complex(a(GO:"filamentous actin"), p(HGNC:MAPT, frag("254_284"))) View Subject | View Object

In addition, attachment of a phosphate group to S262 in the peptide Tau (254–284) decreased the affinity of the peptide for F-actin (Supplementary Fig. 1) and lowered the amount of Tau (254–284)-promoted actin bundles (Fig. 4f) PubMed:29215007

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Annotations
Confidence
High

Out-Edges 2

complex(a(GO:"filamentous actin"), p(HGNC:MAPT, frag("254_284"))) hasComponent a(GO:"filamentous actin") View Subject | View Object

Appears in Networks:

complex(a(GO:"filamentous actin"), p(HGNC:MAPT, frag("254_284"))) hasComponent p(HGNC:MAPT, frag("254_284")) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.