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p(HBP:"Tau isoform C (410 aa)")

Equivalencies: 0 | Classes: 1 | Children: 0 | Explore

Entity

Name
Tau isoform C (410 aa)
Namespace
HBP
Namespace Version
20181023
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/3074b85b858455d8eeb76cfcdef685ced19bbe11/export/hbp-names.belns

Appears in Networks 5

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications v1.0.0

Analysis of Isoform-specific Tau Aggregates Suggests a Common Toxic Mechanism Involving Similar Pathological Conformations and Axonal Transport Inhibition v1.0.1

Tau Biochemistry v1.2.5

Tau Biochemistry Section of NESTOR

Tau Modifications v1.9.5

Tau Modifications Sections of NESTOR

Tau in physiology and pathology v1.0.0

In-Edges 2

p(HGNC:MAPT) hasMember p(HBP:"Tau isoform C (410 aa)") View Subject | View Object

Appears in Networks:

p(HGNC:FUS) decreases p(HBP:"Tau isoform C (410 aa)") View Subject | View Object

Indeed, knockdown of FUS increases the expression of the 2N and 4R tau isoforms, providing a possible link between frontotemporal lobar degeneration-FUS (FTLDFUS; a subtype of FTD characterized by FUS inclusions in neurons and glia) and FTLD-tau (a tauopathy). PubMed:26631930

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Out-Edges 4

p(HBP:"Tau isoform C (410 aa)") hasVariant p(HBP:"Tau isoform C (410 aa)", pmod(HBP:"protein aggregation")) View Subject | View Object

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p(HBP:"Tau isoform C (410 aa)") partOf a(MESH:Brain) View Subject | View Object

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p(HBP:"Tau isoform C (410 aa)") isA p(HBP:"3R tau") View Subject | View Object

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p(HBP:"Tau isoform C (410 aa)") hasVariant p(HBP:"Tau isoform C (410 aa)", pmod(HBP:glycation)) View Subject | View Object

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.