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p(HGNC:MAPT, pmod(HBP:nitration))

Equivalencies: 0 | Classes: 0 | Children: 3 | Explore

Entity

Name
MAPT
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 2

Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease v1.0.0

Tau Modifications v1.9.5

Tau Modifications Sections of NESTOR

In-Edges 6

p(HGNC:MAPT) hasVariant p(HGNC:MAPT, pmod(HBP:nitration)) View Subject | View Object

Appears in Networks:

path(MESH:"Neurofibrillary Tangles") association p(HGNC:MAPT, pmod(HBP:nitration)) View Subject | View Object

The predominant post-translational modification of tau in the NFTs is phosphorylation; however numerous modifications have been noted including truncation, acetylation, nitration, and several others (2–4). PubMed:24027553

Appears in Networks:
Annotations
Text Location
Review

a(CHEBI:peroxynitrite) increases p(HGNC:MAPT, pmod(HBP:nitration)) View Subject | View Object

Previously, we showed that peroxynitrite (ONOO-) induces the oxidative 3,3¢- dityrosine (3,3¢-DT) cross-linking and site-selective nitration of tau monomers [Reynolds et al. (2005) PubMed:16566606

Appears in Networks:

p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 18)) isA p(HGNC:MAPT, pmod(HBP:nitration)) View Subject | View Object

Appears in Networks:

p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 197)) isA p(HGNC:MAPT, pmod(HBP:nitration)) View Subject | View Object

Appears in Networks:

p(HGNC:MAPT, pmod(HBP:nitration, Tyr, 29)) isA p(HGNC:MAPT, pmod(HBP:nitration)) View Subject | View Object

Appears in Networks:

Out-Edges 1

p(HGNC:MAPT, pmod(HBP:nitration)) association path(MESH:"Neurofibrillary Tangles") View Subject | View Object

The predominant post-translational modification of tau in the NFTs is phosphorylation; however numerous modifications have been noted including truncation, acetylation, nitration, and several others (2–4). PubMed:24027553

Appears in Networks:
Annotations
Text Location
Review

About

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.