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  3. p(HGNC:MAPT, frag("277_283"))

p(HGNC:MAPT, frag("277_283"))

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
MAPT
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau v1.0.0

In-Edges 2

p(HGNC:MAPT) hasVariant p(HGNC:MAPT, frag("277_283")) View Subject | View Object

Appears in Networks:

complex(a(GO:"filamentous actin"), p(HGNC:MAPT, frag("277_283"))) hasComponent p(HGNC:MAPT, frag("277_283")) View Subject | View Object

Appears in Networks:

Out-Edges 2

p(HGNC:MAPT, frag("277_283")) increases bp(MESH:"Protein Structure, Secondary") View Subject | View Object

In contrast, medium-range NOE cross-peaks, which are specific for secondary structure, were observed for residues ~260 to ~268 and residues ~277 to ~283 PubMed:29215007

Appears in Networks:
Annotations
Confidence
High

p(HGNC:MAPT, frag("277_283")) increases bp(MESH:"Protein Conformation, alpha-Helical") View Subject | View Object

In some of the other conformers of Tau (254–290), however, residues 261–265 were identified not as α- helix but as 3–10 helix, while residues 277–283 were assigned to α-helix PubMed:29215007

Appears in Networks:
Annotations
Confidence
High

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.