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bp(GO:"nitric oxide-cGMP-mediated signaling pathway")

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Entity

Name
nitric oxide-cGMP-mediated signaling pathway
Namespace
go
Namespace Version
20180921
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/go-names.belns

Appears in Networks 1

Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

In-Edges 0

Out-Edges 1

bp(GO:"nitric oxide-cGMP-mediated signaling pathway") increases bp(GO:vasodilation) View Subject | View Object

As such, it nitrosylates the haem-moiety of guanylate cyclase, thereby stimulating formation of cyclic guanine monophosphate (cGMP), which then initiates calcium-dependent vasodilation (Olson et al, 2004). PubMed:25307023

Appears in Networks:
Annotations
Cell Ontology (CL)
erythrocyte
MeSH
Plasma
MeSH
Urine
MeSH
Anemia, Hemolytic, Autoimmune
Text Location
Review

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If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.