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  3. path(MESH:"Diabetes Mellitus")

path(MESH:"Diabetes Mellitus")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
Diabetes Mellitus
Namespace
mesh
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/mesh-names.belns

Appears in Networks 3

Amyloid β oligomers (AβOs) in Alzheimer’s disease v1.0.0

Clearance systems in the brain-implications for Alzheimer disease. v1.0.1

Clearance of Amyloid Beta and Tau in Alzheimer’s Disease:from Mechanisms to Therapy v1.0.1

In-Edges 3

a(CHEBI:"amyloid-beta") positiveCorrelation path(MESH:"Diabetes Mellitus") View Subject | View Object

Meanwhile, an animal experiment showed that IDE expression will descend with age and diabetes, then resulting in Aβ deposition (Kochkina et al. 2015) PubMed:29626319

Appears in Networks:

path(MESH:"Alzheimer Disease") association path(MESH:"Diabetes Mellitus") View Subject | View Object

Known envi- ronmental risk factors for LOAD include cardiovascular disease, and factors conferring a risk of cardiovascu- lar disease, such as diabetes mellitus and hypertension. Head trauma, physical and mental inactivity, and sleep impairment are additional risk factors for LOAD PubMed:26195256

Appears in Networks:

p(HGNC:IDE) negativeCorrelation path(MESH:"Diabetes Mellitus") View Subject | View Object

Meanwhile, an animal experiment showed that IDE expression will descend with age and diabetes, then resulting in Aβ deposition (Kochkina et al. 2015) PubMed:29626319

Appears in Networks:

Out-Edges 4

path(MESH:"Diabetes Mellitus") increases path(MESH:"Alzheimer Disease") View Subject | View Object

The risk factors of AD include: increasing age, vascular factors such as smoking, obesity, and diabetes (Reitz and Mayeux 2014) as well as genetic mutations. PubMed:29196815

Appears in Networks:
Annotations
Confidence
High

path(MESH:"Diabetes Mellitus") association path(MESH:"Alzheimer Disease") View Subject | View Object

Known envi- ronmental risk factors for LOAD include cardiovascular disease, and factors conferring a risk of cardiovascu- lar disease, such as diabetes mellitus and hypertension. Head trauma, physical and mental inactivity, and sleep impairment are additional risk factors for LOAD PubMed:26195256

Appears in Networks:

path(MESH:"Diabetes Mellitus") negativeCorrelation p(HGNC:IDE) View Subject | View Object

Meanwhile, an animal experiment showed that IDE expression will descend with age and diabetes, then resulting in Aβ deposition (Kochkina et al. 2015) PubMed:29626319

Appears in Networks:

path(MESH:"Diabetes Mellitus") positiveCorrelation a(CHEBI:"amyloid-beta") View Subject | View Object

Meanwhile, an animal experiment showed that IDE expression will descend with age and diabetes, then resulting in Aβ deposition (Kochkina et al. 2015) PubMed:29626319

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.