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p(HGNC:IRS1)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
IRS1
Namespace
hgnc
Namespace Version
20180828
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/1b20f0637c395f8aa89c2e2e342d7b704062c242/external/hgnc-symbols.belns

Appears in Networks 1

Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications v1.0.0

In-Edges 2

bp(GO:"GO:0014065") association p(HGNC:IRS1) View Subject | View Object

A second downstream pathway is the PI3K/Akt pathway that regulates neurotrophin-mediated survival responses in PC12 cells [90,91]. Regulation of this pathway involves upstream elements including Ras/Gab1/IRS1 [92,93]. PubMed:18986241

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
PC12
MeSH
Cognitive Dysfunction

bp(GO:"GO:0043491") association p(HGNC:IRS1) View Subject | View Object

A second downstream pathway is the PI3K/Akt pathway that regulates neurotrophin-mediated survival responses in PC12 cells [90,91]. Regulation of this pathway involves upstream elements including Ras/Gab1/IRS1 [92,93]. PubMed:18986241

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
PC12
MeSH
Cognitive Dysfunction

Out-Edges 2

p(HGNC:IRS1) association bp(GO:"GO:0014065") View Subject | View Object

A second downstream pathway is the PI3K/Akt pathway that regulates neurotrophin-mediated survival responses in PC12 cells [90,91]. Regulation of this pathway involves upstream elements including Ras/Gab1/IRS1 [92,93]. PubMed:18986241

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
PC12
MeSH
Cognitive Dysfunction

p(HGNC:IRS1) association bp(GO:"GO:0043491") View Subject | View Object

A second downstream pathway is the PI3K/Akt pathway that regulates neurotrophin-mediated survival responses in PC12 cells [90,91]. Regulation of this pathway involves upstream elements including Ras/Gab1/IRS1 [92,93]. PubMed:18986241

Appears in Networks:
Annotations
Experimental Factor Ontology (EFO)
PC12
MeSH
Cognitive Dysfunction

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.