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Heme Curation v0.0.1-dev

Mechanistic knowledge surrounding heme

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complex(a(CHEBI:apocynin), a(CHEBI:heme)) decreases p(MGI:Slc40a1) View Subject | View Object

We showed that cotreatment of macrophages with heme and apocynin (Fig. 7E), as well as with heme and allopurinol (Fig. 7F), fully prevented ferroportin induction by heme. These data revealed that inhibiting superoxide at its production site is an effective way to counteract heme-mediated ferroportin induction. PubMed:29212341

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