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a(CHEBI:"(-)-lobeline")

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
(-)-lobeline
Namespace
chebi
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/chebi-names.belns

Appears in Networks 1

Discriminative Stimulus Properties of S(−)-Nicotine: “A Drug for All Seasons v1.0.0

In-Edges 1

complex(a(CHEBI:"(-)-lobeline"), a(MESH:"nicotinic receptor alpha4beta2")) hasComponent a(CHEBI:"(-)-lobeline") View Subject | View Object

Appears in Networks:

Out-Edges 3

a(CHEBI:"(-)-lobeline") increases complex(a(CHEBI:"(-)-lobeline"), a(MESH:"nicotinic receptor alpha4beta2")) View Subject | View Object

Lobeline binds with high affinity to α4β2 nAChRs and displays mixed receptor agonist/antagonist actions (e.g., [150–154]). PubMed:28391535

Appears in Networks:

a(CHEBI:"(-)-lobeline") decreases act(a(CHEBI:nicotine)) View Subject | View Object

Lobeline has, however, been shown to antagonize partially the stimulus effects of (-)-nicotine and S(+)-methamphetamine ([64, 160]; but see [66]). PubMed:28391535

Appears in Networks:

a(CHEBI:"(-)-lobeline") decreases act(a(CHEBI:methamphetamine)) View Subject | View Object

Lobeline has, however, been shown to antagonize partially the stimulus effects of (-)-nicotine and S(+)-methamphetamine ([64, 160]; but see [66]). PubMed:28391535

Appears in Networks:

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.