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p(HGNC:GRIA2)

Equivalencies: 0 | Classes: 0 | Children: 0 | Explore

Entity

Name
GRIA2
Namespace
hgnc
Namespace Version
20180906
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/b46b65c3da259b6e86026514dfececab7c22a11b/external/hgnc-names.belns

Appears in Networks 1

Amyloid β oligomers (AβOs) in Alzheimer’s disease v1.0.0

In-Edges 1

a(HBP:HBP00074) regulates tloc(p(HGNC:GRIA2), fromLoc(GO:"extracellular region"), toLoc(GO:intracellular)) View Subject | View Object

Soluble AβOs, but not monomers, mediate the internalization of the GluA1/GluA2 subunits by endocytosis (Zhang et al. 2011), leading to synaptic dysfunction (Hsieh et al. 2006). PubMed:29196815

Appears in Networks:
Annotations
MeSH
Extracellular Space
Cell Ontology (CL)
neuron
Confidence
Medium

Out-Edges 0

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.