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a(CHEBI:melatonin)

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Entity

Name
melatonin
Namespace
chebi
Namespace Version
20190224
Namespace URL
https://raw.githubusercontent.com/pharmacome/terminology/c328ad964c08967a0417a887510b97b965a62fa5/external/chebi-names.belns

Appears in Networks 1

Upstream regulators and downstream effectors of NF-κBinAlzheimer's disease v1.0.0

In-Edges 0

Out-Edges 2

a(CHEBI:melatonin) decreases p(HGNC:NFKBIA, pmod(Ph, Tyr, 42)) View Subject | View Object

The antioxidants LY231617, and melatonin pro- tect the neurons against the insult and prevented the Tyr42 phosphorylation of IκBα, which acts to protect the neurons against physiological injury by repressing the insult-induced oxidative stress activation of transcription factor NF-κB [86]. PubMed:27288790

Appears in Networks:
Annotations
MeSH
Cerebral Cortex
MeSH
Hippocampus

a(CHEBI:melatonin) decreases act(p(FPLX:NFkappaB)) View Subject | View Object

The antioxidants LY231617, and melatonin pro- tect the neurons against the insult and prevented the Tyr42 phosphorylation of IκBα, which acts to protect the neurons against physiological injury by repressing the insult-induced oxidative stress activation of transcription factor NF-κB [86]. PubMed:27288790

Appears in Networks:
Annotations
MeSH
Cerebral Cortex
MeSH
Hippocampus

About

BEL Commons is developed and maintained in an academic capacity by Charles Tapley Hoyt and Daniel Domingo-Fernández at the Fraunhofer SCAI Department of Bioinformatics with support from the IMI project, AETIONOMY. It is built on top of PyBEL, an open source project. Please feel free to contact us here to give us feedback or report any issues. Also, see our Publishing Notes and Data Protection information.

If you find BEL Commons useful in your work, please consider citing: Hoyt, C. T., Domingo-Fernández, D., & Hofmann-Apitius, M. (2018). BEL Commons: an environment for exploration and analysis of networks encoded in Biological Expression Language. Database, 2018(3), 1–11.